The motor evoked potential is a neurophysiologic test designed to examine the function of the motor nervous system. It is performed by stimulating the motor cortex and then the muscle motor complex potentials recorded from the contralateral target muscle. Motor evoked potentials are a non-invasive test that examines the transmission pathways of the autonomic nervous system from the cortex to the muscles, reflecting the overall synchronization and integrity of the conduction pathways. It is an effective electrophysiological method with excellent sensitivity and specificity for monitoring the integrity of the motor nervous system. Motor evoked potential examination can be used for the diagnosis of spinal cord disease, which can directly reflect the functional integrity of the motor system, and therefore help to determine the presence of motor system lesions. Motor evoked potentials can be used to determine the prognosis of patients with motor system disorders, and its latency prolongation and wave amplitude decrease are proportional to the number of motor cells damaged in the anterior horn of the spinal cord and the degree of destruction, and the degree of demyelination of white matter fibers. Clinically, the latency and amplitude of motor evoked potentials can be observed to determine the degree of damage to the spinal cord motor cells and the prognosis. Motor evoked potential monitoring can also be used for intraoperative monitoring. With the expansion of spinal surgery, the number of patients with postoperative complications of spinal cord injury has increased significantly, and intraoperative monitoring can minimize or avoid this complication.