The stomach orifice, or cardia, is the part of the esophagus that connects to the stomach and serves as the outlet of the esophagus and the entrance to the stomach. Gastric orifice pain is considered to be caused by esophagitis, gastric ulcer, gastric cancer and so on. 1. Esophagitis: refers to the inflammation caused by the damage of esophageal mucosa caused by stomach acid, bile, esophageal foreign body, etc. The main symptoms are acid reflux, heartburn, chest pain and difficulty in swallowing, etc. The cardia is the entrance to the stomach. The cardia is the entrance to the stomach, and it is very easy to damage the esophageal mucosa due to the reflux of gastric acid, food and other gastric contents. 2. Gastric ulcer: It is a common disease in the digestive system and can occur in any part of the stomach. If the ulcer is located in the cardia, the damaged gastric mucosa can cause pain due to inflammation, food and other stimuli, and if the condition is more serious, the patient can also have spontaneous cardia pain. 3. Gastric cancer: Cancer that occurs in the stomach, the lesion can exist in any part of the stomach, such as the gastric body, gastric sinus, etc. The most important symptom is abdominal pain, and in the late stage, there can be emaciation, anemia, anorexia, etc. If the tumor tissue is located in the cardia, it can cause pain due to inflammation, food and other stimuli. If the tumor tissue happens to be located at the cardia, it can cause cardia pain. If the tumor tissue is located in the cardia, it can cause cardia pain. It is recommended to consult a doctor immediately, make a clear diagnosis, and then carry out targeted treatment.