Nucleic acid testing refers to the nucleic acid test for C. neoformans, which cannot be done by oneself, but can be done by antigenic self-testing. There is no such thing as self-testing for nucleic acid, and the current methods of nucleic acid testing include nasopharyngeal swabs, oropharyngeal swabs, serologic tests and anal swabs. And nucleic acid testing must be trained and qualified inspection and quarantine personnel for sampling, transportation, to a professional laboratory for experimental operations, and finally in accordance with national regulations and procedures to enter the results of the data and published, so self-test nucleic acid can not be realized. Antigen testing is suitable for self-testing for infection with the new coronavirus. The antigen test refers to the collection of respiratory secretions from the mouth and nose by the individual, and then the specimen is dropped into the kit according to the requirements, and the viral proteins that may be present in the specimen will combine with the antibodies in the test kit to form an antibody-antigen complex, which will determine whether or not it is infected by the change in color. Currently, the antigen test is relatively simple and easy to operate, but it is only suitable for the stage of acute infection or high-risk, high-prevalence aggregation of infected populations, with relatively low sensitivity, and the results of the body when the virus is lower than the lower limit of the accuracy of the results are generally poor, and nucleic acid testing is still required. Tips] The “new coronary pneumonia, new coronary virus pneumonia” mentioned in this article has been renamed to “new coronary virus infection” on December 26, 2022, as announced by the National Health Commission.