Newborns do not eat milk for four or five hours, if the baby has no other discomfort, good growth and development is normal; if the baby has overflow, diarrhea, etc., it may be indigestion caused by loss of appetite, it is not normal. Newborns usually breastfeed on demand. If the baby eats a normal amount of milk, normal bowel movements, sleeps peacefully, grows and develops well, and has no symptoms of discomfort, it is normal for the baby not to eat milk for four or five hours occasionally. In addition, newborns usually wake up less often at night, feeding time will be extended accordingly, this time four or five hours without milk is also normal. If the newborn does not eat for four or five hours and at the same time eat significantly less, and there is abdominal distension, increased exhaust, sleep is not peaceful, easy to cry and so on, and even vomiting, overflow of milk, diarrhea, stools more often or constipation, then it may be caused by indigestion. If the newborn does not eat milk for four or five hours, accompanied by discomfort, should be taken to the hospital to identify the cause and follow the doctor’s instructions for treatment.