The vast majority of gallbladder polyps do not have clinical symptoms, but a small number of patients may experience pain in the right upper abdomen, which may also be accompanied by nausea, vomiting, and loss of appetite. The causes of this condition are, on the one hand, likely to be non-stone gallbladder polyps caused by gallbladder polyps, which may be closely related to the location of the polyps, such as those located at the neck of the gallbladder or the gallbladder duct. On the other hand it may be related to gallbladder polyps that grow too fast or even become cancerous. Regardless of the cause of the pain, if it is diagnosed to be caused by gallbladder polyps, surgery should be considered promptly, with laparoscopic cholecystectomy being the first choice. For patients with suspected cancer, a rapid pathological examination should be performed intraoperatively. In addition, gallbladder polyps may also cause pancreatitis, which is much less common clinically, mainly manifested as left upper abdominal pain, which may be related to bile duct anatomical variation or abnormal pressure, and timely surgical removal of the gallbladder should also be considered.