Enlargement of the left atrium and left ventricle may increase the risk of developing cardiac insufficiency, pulmonary stasis, and pulmonary hypertension, and should be taken seriously. Enlargement of the left atrium and left ventricle leads to structural changes in the heart. As the left atrium enlarges, some other structural changes occur secondary to the enlargement of the left atrium, which can easily lead to mitral valve insufficiency, which in turn leads to cardiac insufficiency as the disease progresses. When the pressure in the left atrium increases, it will not only gradually lead to the enlargement of the left atrium, but will also transfer the pressure to the pulmonary veins, resulting in pulmonary stasis, which will transfer the pressure to the pulmonary arteries, resulting in pulmonary hypertension, which will lead to changes in the right heart. When the left atrium and left ventricle are enlarged, it is recommended to consult a doctor for further examination, to clarify the cause with the help of the doctor, and to carry out targeted treatment or therapy.