Patients with premature ovarian failure usually show abnormal menstruation or premature amenorrhea, and may also have low estrogen manifestations, such as hot flashes, night sweats during sleep and other menopause-like manifestations. Symptoms of premature ovarian failure are mainly decreased menstrual flow, delayed menstruation, or even amenorrhea, and some menopausal symptoms, such as hot flashes, sweating, heartburn, insomnia, and forgetfulness. There may also be some urogenital symptoms, such as frequent urination, incomplete urination, etc.; there will also be calcium deficiency, such as osteoporosis, easy to fracture, etc.. The treatment of premature ovarian failure is mainly to control and prevent the complications caused by premature ovarian failure, such as supplemental estrogen and progesterone treatment, which can improve the menstrual symptoms and alleviate the symptoms of unstable vasodilatation caused by the reduction of estrogen. The causes of premature ovarian failure are complex, so it is recommended that patients consult a doctor in a timely manner to clarify the cause of the disease and provide targeted treatment.