The more vitamin E is applied, the darker it gets. This is mainly related to the photosensitivity, or photosensitivity, of vitamin E. Vitamin E is prone to pigmentation of the skin at the site of application under sunlight, so prolonged use may lead to darkening of the skin. Therefore, it is recommended that patients use vitamin E at night to avoid darkening of the skin and reduce melanin production. Vitamin E is a relatively strong antioxidant, skin applied vitamin E lotion or moisturizer, can play a role in moisturizing the skin and protecting the skin, especially in the dry season of autumn and winter, can play a better moisturizing effect, so vitamin E can play a role in moisturizing, but the use of the time must also be used in the right way, patients are advised to use at night.