It is usually difficult to return to normal after craniopharyngioma surgery, and there are usually more obvious complications, such as urolithiasis and blood electrolyte disorders. Craniopharyngioma surgery is one of the more difficult neurosurgical procedures, and it is difficult to achieve total tumor resection, and in most cases, it only serves to alleviate the patient’s symptoms of increased intracranial pressure, endocrine hypoplasia, and visual impairment. The mortality rate of the first surgery for craniopharyngioma in children is around 2%, mainly due to severe hypothalamic injury. Complications caused by hypothalamic injury mainly include uremia, electrolyte disorders, epilepsy, etc., of which the probability of uremia is about 91%, and the probability of blood electrolyte disorders is about 89%, while another long-term complication is hypothalamic obesity, which is seen in about 50% or more of the children. In summary, it is generally difficult to return to the original physical condition after craniopharyngioma surgery, but it is still necessary to follow the doctor’s instructions for reasonable treatment, and the emergence of maladaptation timely consultation.