GFR is the English abbreviation for glomerular filtration rate, which refers to the amount of filtrate produced by the two kidneys per unit of time, and can reflect the glomerular filtration function. The normal value is generally 80~120ml/min.
The common reasons that affect the glomerular filtration rate to make it higher or lower are pregnancy, diabetic nephropathy, hemorrhage, primary glomerular disease and so on.
1. In pregnant women, the plasma flow is higher than usual, so that the glomerular plasma flow is also greatly increased, and the glomerular filtration rate is elevated.
2. In the early stage of diabetic nephropathy, the concentration of glucose content in glomerular plasma is higher, leading to high glomerular filtration and elevated glomerular filtration rate.
3. In hemorrhage, the hydrostatic pressure of glomerular capillaries decreases, leading to a decrease in effective filtration pressure, which in turn leads to a decrease in glomerular filtration rate.
4. Common primary glomerular diseases, such as mesangial proliferative glomerulonephritis, membranous glomerulonephritis, IgA nephropathy, etc. will lead to the damage of the glomerulus and glomerular filtration system, which will lead to the decrease of glomerular filtration rate.
Elevated or decreased GFR needs to go to the nephrology department of the hospital to find out the cause so as not to delay the condition.