The main causes of lymphatic follicle hyperplasia at the root of the tongue are as follows: First, chronic pharyngitis and tonsillitis, inflammation can cause lymphatic follicle hyperplasia at the root of the tongue and enlargement of lymph nodes in the neck. Secondly, inflammation of the lingual papillae at the root of the tongue. The lingual papillae at the root of the tongue are the taste receptors of the human body, and the redness and inflammation of the lingual papillae will cause hyperplasia of the lymphatic follicles at the root of the tongue. Thirdly, lymphatic follicles at the root of the tongue can be enlarged due to ulcers of the tongue mucosa, which occur at the lateral edge of the tongue and at the root of the tongue. Fourth, herpes virus infection leads to herpes cheilitis and herpes stomatitis, both of which can also cause enlargement of lymphatic follicles at the root of the tongue. Fifthly, when the soft tissues around the wisdom teeth are inflamed due to their location near the back of the mouth, pericoronitis can cause enlarged lymph nodes and lymphatic follicle hyperplasia at the root of the tongue.