Vaccines are not recommended for girls aged 12-17 years during menstruation. Vaccines are biological products made by various types of pathogenic microorganisms for preventive inoculation, and the body may experience adverse vaccine reactions after vaccination. If the vaccine is given during menstruation, there may be confusion between adverse vaccine reactions and discomfort caused by menstruation. Therefore, it is recommended to avoid menstruation when giving the vaccine, and you can wait until your menstruation is completely over before receiving the vaccine. After vaccination, some girls may experience adverse reactions to vaccines, such as pain at the injection site, transient fever, body weakness, etc. These adverse reactions usually improve within 2-3 days without special intervention. If the adverse reactions do not improve in three days, you need to go to the hospital as soon as possible to receive targeted treatment from the doctor.