Cough with weight loss is usually one of the symptoms of tuberculosis, a chronic infectious disease caused by Mycobacterium tuberculosis, which can affect many organs, with tuberculosis infection of the lungs being the most common. The most common form of tuberculosis infection is in the lungs. People who excrete the bacilli are an important source of infection. Infection with Mycobacterium tuberculosis does not necessarily cause morbidity, but may cause clinical morbidity when resistance is reduced or cell-mediated metaplasia is increased. If diagnosed promptly and treated appropriately, most cases can be cured clinically. In addition to cough with weight loss, tuberculosis is also associated with the following symptoms, which can be used as a basis for examination and confirmation of the diagnosis: a. Systemic symptoms Systemic symptoms of toxicity include low fever in the afternoon, fatigue, loss of appetite, weight loss, and night sweats. When the lung disease is rapidly progressing and spreading, there may be high fever, and women may have menstrual disorders or amenorrhea. Respiratory system Generally, there is a dry cough or only a small amount of mucus. When there is secondary infection, the sputum is mucus or purulent. About 1/3 of patients have varying degrees of hemoptysis. When the inflammation reaches the wall pleura, there is tingling pain in the corresponding chest wall, which is usually not severe and worsens with breathing and coughing. In chronic severe tuberculosis, respiratory function slows down and dyspnea develops.