Cough with weight loss is usually one of the symptoms of tuberculosis, a chronic infectious disease caused by Mycobacterium tuberculosis, which can affect many organs, with tuberculosis infection of the lungs being the most common. The most common form of tuberculosis infection is in the lungs. People who excrete the bacilli are an important source of infection. Infection with Mycobacterium tuberculosis does not necessarily cause morbidity, but may cause clinical morbidity when resistance is reduced or cell-mediated metaplasia is increased. If diagnosed promptly and treated appropriately, most cases can be cured clinically. The cough is one of the most common symptoms of the respiratory system and is a protective measure that is beneficial to the body. When the respiratory mucosa is stimulated by foreign bodies, inflammation, secretions or allergic factors, it reflexively causes coughing, which helps to eliminate foreign bodies or secretions that have invaded the respiratory tract from outside and eliminate respiratory irritants. Persistent cough is a precursor to lung disease. It takes two to three months to heal once it starts, and no cough medicine seems to help it. 2. Episodic cough Episodic means that it occurs intermittently and does not persist. Episodic cough is a description of a form of attack that has no etiology, so it has no meaning. Most episodic coughs are actually allergic coughs. 3. Cough syncope Cough syncope is the loss of consciousness immediately after a violent cough, with hypotonia and a short period of time. A few patients feel dizzy and dizzy first, and their faces turn from blue to pale and sweating. Patients are mostly obese men after middle age, frequent smokers with bronchitis and emphysema, and children with pertussis or asthma. Most of them follow repeated coughing, and occasionally fainting is seen immediately after a single cough, call, sneeze, yawn, or laughing. Coughing increases intrathoracic pressure, resulting in obstruction of venous return and cardiovascular reflexes play a role in the onset of the disease. Systemic symptoms: Systemic toxicity is manifested by afternoon low-grade fever, malaise, loss of appetite, weight loss, and night sweats. When the pulmonary signs progress rapidly and spread, there may be high fever, and women may have menstrual disorders or amenorrhea. Respiratory system: There is usually a dry cough or only a small amount of mucus. When accompanied by secondary infection, the sputum is mucous or purulent. About 1/3 of patients have varying degrees of hemoptysis. When inflammation spreads to the mural pleura, there is stabbing pain in the corresponding chest wall, which is usually not severe and worsens with breathing and coughing. In chronic severe tuberculosis, respiratory function slows down and dyspnea develops.