Progesterone should not be taken after menstruation. Progesterone is a progesterone drug, which can be used for the treatment of luteal insufficiency and promotion of menstruation, etc. Taking progesterone drugs after menstruation is likely to cause endocrine disorders. Under normal physiological conditions, the estrogen and progesterone levels increase after ovulation, and on the eve of menstruation, the estrogen and progesterone levels drop sharply, and the endometrium loses hormonal support and bleeds, which is also known as menstruation. If progesterone is taken during menstruation, it will cause the progesterone level, which should be low, to rise, affecting the normal secretion function of the ovaries and causing endocrine disorders leading to menstrual disorders. It is recommended not to take estrogen or progesterone drugs at will, but if you need to take them because of illness, it is best to take them under the guidance of a doctor. During menstruation, you should pay attention to a reasonable diet, pay attention to perineal hygiene, and change sanitary napkins regularly.