High uric acid is caused by the body’s abnormal metabolism of purine substances, resulting in abnormal uric acid excretion, or excessive production. Clinically, there are two types: primary and secondary. Primary is caused by inborn abnormalities of purine metabolism, often accompanied by obesity, type 2 diabetes, dyslipidemia, hypertension, atherosclerosis and coronary heart disease. Secondary is caused by certain systemic diseases, such as leukemia, multiple myeloma, chronic kidney disease, and taking certain drugs, which inhibit uric acid excretion. Among patients with high blood uric acid, 5-12% will develop gout, with recurrent painful arthritis, interstitial nephritis and gouty stone formation, and in severe cases, it will be accompanied by joint deformity or uric acid urinary tract stones. Patients with high uric acid should first control their diet, which should be based on low purine foods and strictly control foods with high purine content. Daily to drink more water, so that the daily urine volume should reach more than 2000ml; gout recurrence and blood uric acid increased significantly and accompanied by cardiovascular and cerebrovascular disease, etc., should be orally lowering the uric acid drug treatment.