Epithelial hyperplasia is the process of transformation of one type of differentiated tissue into another, not a direct transformation from a differentiated cell to another, but, on the contrary, formed by the differentiation of undifferentiated cells with the ability to divide in the other direction, which generally can only be transformed into cells with similar characteristics. The common ones are squamous epithelial hyperplasia and intestinal epithelial hyperplasia.
1. Squamous Epithelial Hyperplasia: The ciliated columnar epithelium of the tracheal and bronchial mucosa can be transformed into squamous epithelium in long-term smokers or when damaged by chronic inflammation. If it persists, it may become the basis for bronchial squamous cell carcinoma. Squamous epithelial hyperplasia can enhance local resistance, but it also loses the function of the original epithelium.
2. Intestinal epithelial hyperplasia: this kind of hyperplasia is common in the gastric body or gastric sinus. Intestinal metaplasia is common in chronic atrophic gastritis, gastric ulcer and mucosal regeneration after gastric mucosal erosion.
Patients with or without symptoms need regular review, such as the appearance of atypical hyperplasia should be treated in a timely manner to avoid delaying the condition.