After taking cold medicine, some patients will have the adverse reaction of sleepiness, most commonly because of the side effects that can occur when cold medicine is compounded with paracetamol. Paracetamol is an H1 receptor antagonist, drowsiness is the most common side effect, and even appear to have mental depression, drowsiness, this time should drink more warm boiled water, through urination, sweating, etc., can accelerate the metabolism of cold medicine in the body, can make paracetamol as soon as possible to be able to discharge most of the body, but also can replace the cold medicine does not contain paracetamol ingredients, but contains caffeine ingredients cold medicine, which not only has a certain cough suppressant effect, but also has a certain effect of fighting drowsiness, fatigue and other side effects of paracetamol.