At present, there is no specific drug that can completely cure gastric ulcer, this disease is mainly related to drug abuse and Helicobacter pylori infection, and should be used for the cause of the disease. 1. Abuse of drugs: Abuse of non-steroidal anti-inflammatory drugs (NSAIDs) may cause this disease. Patients should stop abusing drugs in time and apply omeprazole, aluminum hydroxide and other drugs under the guidance of doctors for treatment. After using the drugs, patients may experience adverse reactions such as nausea, headache, insomnia, and rash. Severe renal insufficiency and those who are allergic to the drugs should disable such drugs. 2. Helicobacter pylori infection: quadruple therapy should be adopted for intervention, i.e., proton pump inhibition + bismuth + two antibiotic drugs for joint use, such as omeprazole + bismuth pectin + levofloxacin + metronidazole synchronized application. Adverse reactions such as rash and constipation may be triggered after the administration of the drug. Special groups such as liver and kidney insufficiency, allergy to the above drugs, infants and young children should be forbidden to take this therapy. For patients, they should seek medical examination as early as possible to confirm the cause and condition of the disease, and then use the medication under the guidance of the doctor, do not apply it arbitrarily. If any adverse reaction occurs after the use of the drug, it is necessary to seek medical treatment in time.