What does low white blood cells, neutrophils mean? Leukocytes, neutrophils are normal cells in the body and its normal value is 4-12 x 10^9/L. Leukocytes are the molecular warriors in the body that fight against bacterial infections outside as well as viral infections. lowered leukocytes, lowered neutrophils are when leukocytes are below 4 x 10^9/L or neutrophils are below 2 x 10^9/L becoming leukocytes or neutrophils decreased. It is mainly seen in, first, suppression of the hematopoietic function of the bone marrow, because the bone marrow can produce leukocytes and make white blood cells, and if the function of the bone marrow is suppressed, this is when the white blood cells are lowered. Second, excessive depletion of leukocytes, including after infection and sepsis, which can lead to excessive depletion of leukocytes, because when leukocytes are antagonistic to bacteria in the body, they are also damaged and can become lysed. Third, various hematological diseases can lead to a decrease in white blood cells. For example, aplastic anemia, multiple myeloma, myelodysplastic syndrome, and many other leukemias can cause a decrease in white blood cells. In summary, a decrease in leukocytes and neutrophils is what we call a decrease in leukocytes and neutrophils when the leukocytes are below 4 x 10^9/L and the neutrophils are less than 2 x 10^9/L.