Rabies is a zoonotic acute infectious disease caused by the rabies virus that invades the central nervous system, and can be transmitted by both humans and domestic animals, and is also known as hydrophobia because the clinical manifestation is characterized by fear of water. Rabies is spread by cat and dog bites, scratches or licking to the broken skin wound. If the cat or dog bite or scratch wound has broken skin, this situation belongs to rabies exposure, the wound needs to be washed with soap and water, disinfected with iodine, and go to the CDC as soon as possible for rabies vaccination. If the wound is still bleeding, this case is considered tertiary exposure, in addition to rabies vaccine, but also need to be injected with rabies human immunoglobulin to prevent rabies, the general rabies vaccine is divided into five injections or four injections, usually injected with a full course of rabies vaccine will not be infected with rabies. If you are bitten or scratched by a cat or dog, and the wound has broken skin, without rabies vaccination, there is a risk of rabies transmission.