Weak spermatozoa are usually fertile and patients can improve their chances of fertility with active treatment. Weak spermatozoa is a condition in which less than 32% of spermatozoa move forward in the semen parameters, and its cause may be due to chromosomal abnormality, endocrine abnormality, infection, micronutrient deficiency, smoking and other factors. Usually patients do not have obvious systemic symptoms, which may manifest as difficulty in getting pregnant. Generally, patients with weak spermatozoa have the possibility of fertility, and if patients standardize the relevant treatment, they can achieve the possibility of natural fertility. If the patient has an infection, you can take oral antibiotics such as ceftriaxone sodium, azithromycin, or oral vasodilator drugs, such as pancreatic kallikrein releasing enzyme, as well as oral vitamins such as vitamin E, vitamin C and other vitamins under the guidance of the doctor. If necessary, surgical treatment can also be taken, such as high ligation of the internal spermatic vein, pituitary tumor surgery. It is recommended that patients with weak spermatozoa should go to the hospital in time to find out the primary cause of the disease and treat the symptoms, which can improve the quality of sperm and achieve natural fertility.