Ovarian cancer ascites is mainly caused by cancer invading the peritoneum or lymphatic system, or cancer leading to hypoproteinemia, and abdominal chemotherapy is a kind of therapeutic program for intra-abdominal metastasis, and there is no obvious relationship between the two. Ovarian cancer ascites is mainly due to the metastatic spread of ovarian cancer cells in the peritoneal cavity and invasion of lymphatic system. Tumor cells proliferate in lymphatic vessels and thus block lymphatic reflux, resulting in a large amount of lymphatic fluid oozing out of the peritoneal cavity and formation of ascites. In addition, cancer is a consumptive disease, which may lead to hypoproteinemia and cause ascites. Intraperitoneal chemotherapy is a treatment for ovarian cancer metastasis in the abdominal cavity, which promotes the killing of tumor cells by instilling chemotherapeutic drugs into the abdominal cavity in order to reduce ascites. Therefore, there is no obvious relationship between the production of ascites and abdominal chemotherapy. It is recommended to consult a professional doctor and take standardized diagnosis and treatment in order to alleviate the condition and improve the prognosis.