Anti-inflammatory injections (antibiotics) after surgery for perianal abscesses are usually given for 2-7 days depending on the situation, but this cannot be generalized and needs to be based on factors such as the patient’s degree of infection and recovery. Perianal abscess is an acute suppurative infection that occurs in the soft tissues around the anal canal and rectum or in the interstitial space around them, with perianal distension, swelling and pain, anal drop sensation, and localized breakthrough pus as the main clinical manifestations, and currently the main treatment is to perform perianal abscess incision and drainage. Antibiotic injection after perianal abscess surgery is mainly to avoid new infections caused by necrotic tissues, usually need to be used for 2-7 days, mainly based on the patient’s physical condition, condition and recovery and other factors. Commonly used broad-spectrum antibiotics to give anti-infection treatment, such as ceftriaxone sodium, amoxicillin, ciprofloxacin and other drugs, but also according to the blood culture or drug sensitivity test to choose the effective use of drugs. At the same time, we should adjust the life and diet habits, avoid mental stress and fatigue, pay attention to keep the stool moist during the recovery period to avoid bleeding caused by dry stools, avoid spicy and stimulating food, and regularly disinfect and change the medication. If there is any discomfort after the operation, you should communicate with the attending doctor immediately, and under the doctor’s guidance, give treatment as early as possible, and actively cooperate with the treatment and regular follow-up.