Leukemia is associated with radiation, chemical factors, genetic factors, other blood diseases, etc. There is no clear “most” susceptible group of people to get leukemia. 1. Radiation: Adult acute leukemia can be induced by high-dose radiotherapy or chemotherapy, exposure to high levels of radiation in the environment, such as nuclear power plant leakage accidents. 2. Chemical factors: long-term exposure to benzene and organic solvents containing benzene, or certain pesticides, formaldehyde and nitrosamines may induce the disease. 3. Genetic factors: People with a family history of leukemia and chromosomal abnormalities have a higher risk of developing leukemia, such as patients with Down’s syndrome. 4. Certain blood disorders: Certain blood disorders may eventually develop into leukemia, such as myelodysplastic syndromes, lymphomas, and multiple myeloma. Consult your hematologist for specific knowledge.