Mycoplasma pneumoniae treatment time is usually about 2 weeks, depending on the specific condition, the course of treatment can be appropriately reduced for milder conditions and extended for more severe conditions. Mycoplasma pneumoniae commonly used drugs are macrolide antibiotics and quinolone antibiotics, macrolide antibiotics including azithromycin, erythromycin, etc., quinolone antibiotics including levofloxacin, moxifloxacin, etc. The treatment process should pay attention to the side effects of drugs and the corresponding contraindications, such as macrolide antibiotics can occur in the gastrointestinal tract side effects, after eating, quinolones age <18 years or >80 years, or have mental illness is prohibited. Mycoplasma pneumoniae is diagnosed by a recent 4-fold or more elevated mycoplasma antibody along with clinical symptoms, such as cough, high fever, headache, nausea, and depression.