Corns on the hands can be eradicated through medication, physical therapy and surgical treatment. 1. Medication: Topical application of some corrosive drugs can achieve the purpose of removing corns, the more commonly used drugs are salicylic acid phenol cream. 2. Physical therapy: including cryotherapy and laser therapy. Cryotherapy is the use of liquid nitrogen’s extremely low temperature, the lesion caused by frostbite, so as to achieve the purpose of removing corns. Laser treatment is the use of laser light and heat to destroy the skin lesions, to become a rapid removal of corns. 3. Surgery: The use of surgical methods to directly remove corns is a fast and effective method. Whichever way you choose to eradicate corns, be sure to have a professional doctor perform the operation.