Sodium vitrate can cover and protect the joint tissues, increase the degree of joint lubrication, inhibit the property change of cartilage by penetrating into the degenerated cartilage, improve the metabolism of degenerated cartilage, and produce pain relief by inhibiting the action of pain mediators on the synovial membrane. Sodium vitrate acts on synovial cells and promotes the formation of high molecular vitric acid, which can improve joint contracture and prevent adhesion of tendons and tendon sheaths, so it is suitable for deformity knee arthropathy as well as periarthritis of shoulder joint. However, it should be noted that it is necessary to prevent drug allergy, abnormal liver function, and patients with skin diseases or infections at the site of administration need to use it with caution. When there is a heavy inflammatory reaction in the joint, the inflammation should be eliminated before using the drug, and the knee joint should be made stationary for a period of time after using the drug, pregnant women as well as lactating women should use it with caution.