Thigh pain does not necessarily have a certain correlation with cancer pain, and of course cancer cannot be completely ruled out. If the patient has localized thigh pain, trauma, inflammation, lumbar condition, etc. should be excluded, and if necessary, imaging examination, such as ultrasound, CT, etc., can be performed to evaluate whether there are localized occupying lesions. If the lumbar spine is not good, the lumbar spine should also be examined, because occupying lesions or injuries in the lumbar spine may lead to nerve compression and cause thigh pain. Cancer-induced thigh pain is often persistent and is not relieved after rest. Therefore, although thigh pain is not a specific clinical symptom of cancer, persistent pain can be examined by imaging tests to rule out the possibility of cancer.