Mesalazine suppositories should be mesalazine suppositories, used for ulcerative colitis effect is better, but the efficacy of individual differences, should be used in accordance with medical advice. Mesalazine suppositories can directly act on the inflammatory intestinal tissues, inhibit leukocyte chemotaxis, and reduce the production of leukotrienes and cytokines. Used in the treatment of ulcerative colitis, can have a better efficacy, but the efficacy of individual differences due to individual physique, condition and other factors. Mesalazine suppository adverse reactions can be seen abdominal discomfort, diarrhea, nausea, headache, vomiting, rash, urticaria, eczema and so on. The drug is contraindicated in those who are allergic to mesalazine or salicylic acid drugs, those with severe liver or kidney impairment, and children under 2 years of age. It should be used regularly under the guidance of a doctor.