Tadalafil side effects exist to lower blood pressure and is mainly used to treat erectile dysfunction, which can cause adverse reactions in the cardiovascular, digestive, and nervous systems. Tadalafil can be used for the treatment of erectile dysfunction and the side effect of lowering blood pressure exists. Tadalafil and alpha-adrenergic receptor blockers are both vasodilators with blood pressure-lowering effects, and their combination can have a superimposed effect on blood pressure, causing significant reductions in blood pressure in some patients when both drugs are used together. Tadalafil can also cause other cardiovascular adverse effects such as angina, chest pain, myocardial infarction, and palpitations. It can also cause arthralgia, neurologic adverse reactions (dizziness, hyperalgesia), digestive adverse reactions (dry mouth, dysphagia, epigastric pain, vomiting), and eye symptoms (blurred vision, eye pain). It is recommended to use tadalafil under medical supervision, not blindly self-medication.