Loss of temperature sensation is one of the symptoms of spinal cord cavitation, which is caused by disruption of the thalamic fibers of the spinal cord. The spinal cavity is often surrounded by gliosis, which is the result of the formation of a tubular cavity in the spinal cord for a variety of reasons. The onset of the disease is slow, and the clinical manifestations are symptoms of nerve damage in the affected spinal cord segments, characterized by hyperalgesia and hyperalgesia with preserved deep sensation and dissociative sensory deficits, as well as motor deficits and neurotrophic deficits associated with damage to the long tracts of the spinal cord. In cases of tumors, astrocytomas or ventricular meningiomas in the gray matter of the spinal cord secrete proteinaceous fluid that accumulates above and below the tumor, widening the diameter of the spinal cord. It is sometimes difficult to distinguish between these tumors, especially when they are located in the lower cervical medulla. However, the course of the tumor progresses faster, radicular pain is common, and nutritional disorders are rare. In early stage, the protein in cerebrospinal fluid is increased, which can be distinguished from this disease. For difficult cases, CT and MRI can be used to differentiate. 2, cervical spine osteoarthropathy can cause muscle atrophy of the upper limbs and long bundle signs, but root pain is common, and segmental sensory disorders at the level of the lesion are rare. Cervical spine radiographs, myelography if necessary, and cervical spine CT or MRI can help confirm the diagnosis. Cervical ribs can cause limited atrophy of the small muscles of the hand and sensory disturbances with or without evidence of subclavian artery compression, and because cervical ribs are often present in spinal cavernous disease, diagnostic confusion can occur. However, sensory deficits caused by cervical ribs are usually limited to the ulnar aspect of the hand and forearm, tactile deficits are more severe than pain deficits, upper arm tendon reflexes are not affected, and there are no long tract signs, which can help establish a diagnosis when a distinction can be made, and cervical spine radiographs can also help establish a diagnosis. 4, ulnar nerve palsy can produce limited atrophy of the interosseous muscles and the two middle earthworm muscles. However, the sensory impairment is relatively mild and limited, and the tactile and pain sensations are also involved. 5, leprosy can cause loss of sensation, muscle atrophy of the upper limbs, finger ulcers. However, there is thickening of the median, ulnar and radial nerves and the brachial plexus nerve trunk, and there can be scattered depigmented spots on the trunk. 6, syphilis Can be suspected of spinal cavernous disease in two ways. In rare proliferative duralgia, upper extremity sensory deficits, atrophy, and weakness and lower extremity cone fasciculation signs can occur, but myelography can show subarachnoid obstruction, and the disease progresses more rapidly than spinal cavernous disease. Syphilitic tumors of the spinal cord can show signs of intramedullary tumors, although the progressive destruction of the disease course is rapid and syphilis seropositive. 7. Amyotrophic lateral sclerosis is not easily confused with spinal cavernous disease because it does not cause sensory abnormalities or sensory deficits. 8. Puncture injury or fracture displacement can sometimes cause intramedullary hemorrhage that accumulates in the same spinal cord plane as spinal cavernous disease, but the history of injury and evidence of spinal injury on radiographs are sufficient to provide a basis for differentiation.