Azithromycin is indicated for the treatment of the following infections caused by sensitive bacteria: lower respiratory tract infections such as bronchitis and pneumonia; skin and soft tissue infections; acute otitis media; and upper respiratory tract infections such as sinusitis, pharyngitis and tonsillitis. There are many side effects and adverse reactions of azithromycin, and children must pay attention to the dosage used when using the drug. (1) Blood and lymphatic system abnormalities may occur after taking the drug: thrombocytopenia. (2) Ear and vagus abnormalities may occur: some patients have experienced hearing impairment including hearing loss, tinnitus or deafness after taking azithromycin. It has been shown that this phenomenon is related to the continued high dose use of this product by patients. By following up these patients, it has been found that most of them can recover their hearing. (3) Gastrointestinal abnormalities may occur: nausea, vomiting, diarrhea, loose stools, abdominal discomfort (pain or cramping), flatulence. (4) Abnormalities of the hepatobiliary system may occur: Azithromycin has been reported to cause hepatitis and biliary jaundice, and occasionally hepatic necrosis and liver failure, but is rarely fatal. (5) Skin and subcutaneous soft tissue abnormalities may occur: allergic reactions including rash and angioneurotic edema. (6) Immune system abnormalities may occur: allergic reactions. (7) Cardiac abnormalities may occur: palpitations and arrhythmias, including ventricular tachycardia. If children experience any of these adverse reactions they should stop taking the drug immediately and seek immediate medical attention.