The possible causes of stinging pain at the urethral orifice when women urinate are: first, the occurrence of periurethritis, when there can be local mucosal redness and swelling, accompanied by mucosal erosion, urine stimulates the relevant erosion of the mucosa when urinating, which can produce a stinging sensation, and can be accompanied by symptoms of frequent urination, urinary urgency, painful urination, which requires a step treatment. Second, the presence of gonorrhea, non-gonococcal urethritis and other diseases, mostly through unclean sexual contact and lead to infection, the infection will appear acute congestion and edema of the mucosa of the urethral orifice, accompanied by increased secretions, accompanied by local stinging sensation, the stinging sensation is especially strengthened when urinating, the need for further confirmation of the diagnosis of the relevant secretion examination. Third, the presence of urethral meatus, polyps and other changes, if combined with infection or combined local mucosal rupture, can show obvious pain, physical examination can be seen in the urethral orifice polyp-like or meatus-like protrusion, accompanied by redness and swelling or with secretions, etc., need to carry out local anti-infection treatment, or meatus, polyps and other excision treatment.