Inflammation of tonsils and colds are different in terms of pathogenesis, clinical manifestations and treatment modalities. 1. Pathogenesis: Tonsillitis is mainly caused by bacterial infection, and its main bacteria include beta-hemolytic streptococcus, staphylococcus and so on. Colds are mainly caused by viral infections, such as rhinovirus, adenovirus, respiratory syncytial virus and so on. 2. Clinical manifestations: inflammation of tonsils manifests as local symptoms of severe sore throat, accompanied by swallowing pain, often radiating to the ear. In some cases, the lymph nodes in the angle of the jaw are enlarged and tender. There may be chills, high fever and other systemic symptoms; and cold, also known as acute rhinitis, mostly manifested as nasal congestion, runny nose, sneezing, etc., nasal discharge is watery at first, and then mucopurulent. Fatigue, headache, chills and other systemic symptoms. 3. Treatment: tonsillitis is generally based on anti-infective treatment, patients can follow the doctor’s instructions to apply antibiotics, such as amoxicillin clavulanate potassium, cefuroxime and other treatment. Colds are mostly treated with antiviral therapy, and patients can take antiviral drugs, such as ribavirin, as prescribed by the doctor at an early stage. It is recommended that patients seek timely medical examination, and actively cooperate with the doctor’s treatment.