The main cause of uncomfortable stomach after pooping may be caused by gastroenteritis, peptic ulcer, gastrointestinal dysfunction, irritable bowel syndrome and other diseases, which can be treated according to different etiologies and in accordance with medical advice. I. Organic lesions: 1. Gastroenteritis: due to bacterial infection leading to inflammatory reactions in the intestine, inflammation stimulates the colonic mucosa, causing painful colonic spasms, which can also cause abdominal pain after defecation. Patients should promptly go to the hospital, improve the colonoscopy, barium meal of the digestive tract and other examinations, can apply domperidone, mosapride to promote gastric motility, omeprazole, ranitidine to protect the gastric mucosa, infectious gastroenteritis can follow medical advice to apply norfloxacin for anti-infective treatment; 2, peptic ulcer: patients can appear regular pain in the upper abdomen, appear after the stool abdominal discomfort, through gastroscopy can be differential diagnosis, after the diagnosis After the diagnosis is confirmed, antacids such as omeprazole and ranitidine can be used to reduce gastric acid secretion, with the application of iron to prevent anemia, and those with severe bleeding need to be treated by gastroscopic intervention for hemostasis; 3, Crohn’s disease: clinical symptoms can be manifested as intermittent spasmodic pain in the right lower abdomen or around the umbilicus, when the lesion involves the rectum, there can be mucopurulent stools, and the pain is not relieved after the stool, and the diagnosis can be confirmed by colonoscopy. In mild cases, aminosalicylic acid preparations can be applied, and in severe cases, hormone therapy can be substituted. Second, non-organic lesions: 1, gastrointestinal dysfunction: due to improper diet leading to gastrointestinal dysfunction, insufficient gastric power leads to food not easily digested and absorbed, accumulating in the gastrointestinal department, which may cause symptoms of abdominal distension and abdominal pain. Daily life should pay attention to dietary hygiene, avoid intake of excessive greasy, cold, spicy and stimulating food, can eat foods rich in dietary fiber, such as celery, spinach, etc. Do not overeat, while reducing the intake of coffee, strong tea and other stimulating beverages, pay attention to warmth and avoid getting cold; 2. Irritable bowel syndrome: patients may have a sense of incompleteness after the stool, accompanied by abdominal pain and diarrhea symptoms. Probiotics can be applied to regulate intestinal flora, montelukast to stop diarrhea, and trimethoprim to relieve spasm and pain, thus relieving symptoms.