Waking up with a swollen face may be caused by physiological factors, renal edema, cardiac edema, malnutrition-type edema, hepatic edema, and so on. Different causes, its swelling method also exists different, mainly for general treatment, drug treatment and so on. 1. Physiological factors: If you wake up with a swollen face due to drinking too much water before going to bed, you can improve your bad habits and improve your health. Improving bad habits, such as regular work and rest, ensuring enough sleep, and avoiding drinking too much water before going to bed, will help to alleviate the problem. 2. Nephrogenic edema: If the swelling is caused by diabetes, nephrotic syndrome, glomerulonephritis and other diseases, you need to treat the original disease. For example, glomerulonephritis, can follow the doctor’s instructions to apply methylprednisolone, prednisone acetate and other immunosuppressants, the application of hydrochlorothiazide, furosemide and other diuretics to reduce swelling. 3. cardiogenic edema: if it is caused by cardiac insufficiency, the face is swollen when waking up. The application of angiotensin-converting enzyme inhibitors can be prescribed by the doctor. With the application of dagliflozin, engliflozin and other drugs. 4. malnutrition edema: if it is caused by malnutrition, waking up with a swollen face. It should pay attention to the reasonable adjustment of the diet structure, and strengthen the dietary nutrition. 5. Hepatogenic edema: for example, by cirrhosis, chronic hepatitis and other diseases, resulting in waking up with a swollen face. The application of ursodeoxycholic acid, thiopronin and other hepatoprotective drugs can be treated. Waking up with a swollen face, avoid blindly abusing drugs, exclude physiological factors, should be timely medical treatment, by the doctor’s guidance treatment and conditioning.