High total bilirubin in liver function may be due to physiological causes or may be due to hepatobiliary diseases, and the specific situation needs to be judged by a doctor. Common causes and treatments are as follows: a. Physiological increase: Physiological jaundice occurs in newborns and is seen as high total bilirubin, which can subside on its own in about a week. In addition, behaviors such as long-term alcohol consumption and strenuous exercise may also cause high total bilirubin. Physiological causes of high bilirubin are generally mildly elevated and can be relieved gradually by adjusting the diet, moderate exercise, and strengthening rest, and can generally decline on their own. Pathological increase: 1, hepatitis: patients due to viruses, bacteria, parasites, drugs, alcohol, autoimmune factors, such as liver cell destruction, liver inflammation, can cause high total bilirubin. In terms of treatment, there are different ways to deal with different types of hepatitis. Chronic viral hepatitis should be treated with antiviral therapy, pharmacological hepatitis should be treated by first stopping the exposure to suspected drugs or toxic substances, alcoholic hepatitis should be treated by quitting alcohol, steatohepatitis should be treated by weight loss, and autoimmune hepatitis should be treated by applying immunosuppressants and hormones. Protecting liver function while also giving hepatoprotective drugs such as glycopyrrolate preparations, silymarin, and dicyclomine during treatment can control the progression of liver inflammation necrosis and fibrosis. For patients with chronic hepatitis, especially with obvious fibrosis or cirrhosis, it is recommended to apply anti-fibrotic drugs, such as Anluo Huafen Wan, compound turtle nail soft liver tablets, etc.; 2, gallstone disease: gallstone disease can also cause high total bilirubin of liver function, such patients will appear jaundice, liver pain and other symptoms, ultrasound examination can be found stone images, it is recommended to seek medical attention in a timely manner, the need for surgical treatment to remove stones or removal of the gallbladder; 3, other: cirrhosis, pancreatic cancer, pancreatic cancer, pancreatic cancer, etc. , other: cirrhosis, pancreatic cancer, liver cancer, biliary obstruction and other lesions may also cause high total bilirubin in liver function, and patients are advised to actively treat them under the guidance of doctors.