The main drugs used for local hemostasis of upper gastrointestinal bleeding are vasoactive drugs and thrombin.
Upper gastrointestinal bleeding, gastrointestinal blood vessel rupture, usually use vasoactive drugs to constrict blood vessels to reduce blood flow, local spray thrombin to promote blood coagulation.
1. Norepinephrine, often given orally or injected under the gastric tube to spray the bleeding point, the mechanism of action is that it can constrict the mucosal blood vessels and play a role in hemostasis.
2. The main component of thrombin is the blood coagulation enzyme isolated and purified from the venom of Brazilian spearhead pit vipers, which only has the function of coagulation without changing the amount of thromboplastin in the blood, and it can be sprayed on the wound of gastric ulcers to assist in stopping hemorrhage.
In addition, acid inhibiting drugs can be added to inhibit the secretion of gastric acid to avoid the gastric acid affecting the coagulation of blood.