Anterior cruciate ligament rupture plus meniscus third-degree injury patients are generally recommended to surgical treatment, supplemented by postoperative plaster immobilization and other general treatment, infrared lamp physiotherapy, drug therapy and other methods. 1. Surgery: Anterior cruciate ligament rupture and third degree meniscus injury generally suggests that the morphology and structure of the meniscus have been damaged, at this time, surgical treatment is needed, and according to the situation, it is decided whether to cut off the meniscus or carry out meniscus suture to preserve the function of the meniscus. 2. General treatment: after the operation, the affected limb should be fixed with plaster or brace, avoiding strenuous activities, and performing straight leg raising and ankle pumping in bed to avoid muscle atrophy and venous thrombosis. 3. Physiotherapy: infrared ray, microwave and other physiotherapy can be carried out locally after the operation to reduce local edema and pain. 4. Medication: When swelling is obvious, medicines such as Mazolin and Mannitol can be used to reduce swelling, and non-steroidal anti-inflammatory painkillers such as Etoricoxib can be used in case of pain. Patients with anterior cruciate ligament rupture and meniscus injury of the third degree are recommended to consult the hospital in time, and choose the appropriate surgical method according to the condition, so as to avoid delaying the treatment and causing adverse consequences. The use of drugs should follow the doctor’s instructions.