Transaminases are located in the hepatocytes and are sensitive markers of hepatocyte injury. Transaminase 900 indicates possible acute or chronic liver injury or biliary tract disease. 1. Acute liver injury: patients with acute hepatitis caused by pharmacological or toxic liver injury, acute ischemic liver injury, acute viral hepatitis, etc., the transaminase may rise rapidly up to 900. 2. patients with long-term chronic liver disease, if the transaminase is elevated up to 900, it indicates that liver insufficiency may occur, or even liver failure condition is aggravated, and even in the short term, it will lead to the deterioration of the patient. 3. patients with bile duct obstruction, acute bile duct injury, can also lead to acute, transient transaminase elevation or continuous elevation. If the patient’s aminotransferase significantly elevated up to 900, need to consult a doctor in a timely manner, to find the cause of the disease, and active treatment, so as not to delay the condition.