What is the difference between streptokinase and urokinase

Streptokinase and urokinase are both enzyme inhibitors and are both anticoagulant drugs. But their actions are different.
Streptokinase is an exogenous fibrinolytic activator with thrombolytic effect, and it is a heterogeneous protein with antigenicity, which can cause allergic reactions. Urokinase is a kind of enzyme protein isolated from healthy human urine or obtained from human kidney tissue culture, which acts directly on fibrinogen and converts it into fibrinolytic enzyme, with no antigenicity and few allergic reactions.
Streptokinase and urokinase pharmacological effects are to promote human fibrinolysis process, in the use of the process, the main adverse effects of the two drugs are bleeding tendency, so it should be careful before use need to check the coagulation function.
Specific medication needs to be determined through the doctor, under the guidance of the doctor according to their own physical condition to carry out the medication, do not self-medication.