Some people think that the treatment of many chronic pains is “closed” and injections, which treat the symptoms but not the root cause. This statement is wrong. The difference between the two is: 1, the mechanism of action is different “closed” the original meaning of the proximal local injection of anesthetic in the lesion, in order to block the adverse stimulus from the lesion into the central interrupt the resulting vicious circle, the adverse stimulus closed in the local and conducive to the relief of the patient’s symptoms and the recovery of the lesion. This meaning emphasizes the role of “nerve reflex”. The therapeutic mechanism of “local block” is not only to block the pain sensation at the lesion site and the afferent of the undesirable stimulus, but also to interrupt the vicious cycle, more importantly, “local block” is to inject some effective therapeutic drugs directly into the lesion. These drugs have the effect of regulating the nerves and dilating the microvasculature of the lesion, and improving the blood circulation of the diseased tissue. These effects facilitate the absorption of inflammatory exudate cells and pain-causing substances, thus facilitating the recovery of the lesion. In addition, it also has the effect of direct treatment of sterile inflammation, reduction of adhesions and softening of scarring. Although the dose of “local block” is small, the local concentration of the drug is large, and it is in direct contact with the lesion, so it is not only effective and long-lasting, but also because the amount of drug going to the whole body is very small, so the reaction of the drug is small, and the side effects are also very low, and there is no need for daily treatment. It is also because the drug is directly injected into the lesion tissue local, distributed to other parts of the body such as the cardiovascular system, the amount is very small, so for some oral, intravenous administration of contraindicated patients, under close observation can also be carefully applied to local injection therapy. 2, the use of different drugs “closed” using a higher concentration of anesthetic, while “local block” generally only use a lower concentration of anesthetic can achieve the therapeutic effect, so there will be no limb dysfunction; in addition, the general “closed” injection of drugs generally contains only anesthetic, while “local block” using some direct therapeutic effect on the lesion tissue drugs, such as vitamin B12. 3, the technical difficulty and efficacy of different “closed “closed” is only the injection of drugs to the proximal end of the pain site or nearby to achieve the purpose, the accuracy requirements are not high, therefore, generally as long as you can play the needle, you can perform the “closed” technical operation. In contrast, “local nerve block” is a technical operation that can only be performed properly by a senior anesthesiologist who has undergone a long period of professional training. Therefore, a clear diagnosis must be made before treatment, the precise location of the lesion must be identified, and the treatment drug must be injected accurately into or around the lesion in order to achieve the desired effect. So the same do a treatment, no professional training and of professional training treatment efficacy is far different. 4, the different requirements for diagnosis “closed” therapy is based on pain closure to block the pain arc continued, the diagnosis before injection is not necessarily clear, the injection site is not necessarily the lesion, so the diagnosis is not clear can also be carried out, often pain relief but the lesion can still have development. Before administering “local block” therapy, the diagnosis must be clear and the location of the lesion must be known, and the drug must be injected into the lesion. “Therefore, “local block” is a non-surgical treatment method that concentrates the advantages of medicine, and fights a war of annihilation and rapid warfare, with fast results and high efficacy and fewer visits to the hospital.