What are the dangers of having high platelets?

  Most people do not know what a high platelet count means. A high platelet count is relatively common and may be due to physiological factors, but if the platelet count is too high, it is time for further tests to clarify the condition.   Significantly high platelet count can be considered as primary thrombocythemia. Primary thrombocythemia is a myeloproliferative disorder of unknown origin that occurs mostly in middle-aged and older adults over 40 years of age, especially those between 50 and 60 years of age.  High platelet count requires examination in a hematology department to confirm the diagnosis of the condition Generally, primary thrombocytosis will have a history of bleeding or (and) thrombosis at multiple sites, a routine blood platelet count greater than 1000 x 109/L, a white blood cell count less than 30 x 109/L, and normal or reduced hemoglobin, but not an increased red blood cell count. Some patients may also have splenomegaly and bone marrow hyperplasia.  If thrombocytosis is detected during physical examination and accompanied by the above symptoms, promptly go to hematology department for bone marrow aspiration examination to confirm the diagnosis. Bone marrow aspiration can identify unexplained increase or decrease in the number of red blood cells, white blood cells, platelets and morphological abnormalities.   The risk of high platelet count: About 20% of patients, especially young patients, are asymptomatic at the onset of the disease and are occasionally diagnosed by further examination for thrombocytosis and splenomegaly. 1/3 of patients present with functional or vasodilatory symptoms including vascular headache, dizziness, blurred vision, burning sensation in the palms and soles of the feet, and numbness at the end. 80% of patients may present with unexplained bleeding and thrombosis. Bleeding is often spontaneous and can be recurrent. Gastrointestinal bleeding is common, as well as nasal and gingival bleeding, hematuria, respiratory bleeding, skin and mucosal petechiae, but purpura is rare. Sometimes it can be detected by persistent bleeding after surgery. Occasionally, cerebral hemorrhage occurs, causing death. The incidence of thrombosis is less frequent than bleeding.  Primary thrombocythemia is not common in daily life, and many patients are examined and find elevated values of their own platelets, but do not detect the condition in time.  How high is a platelet count to confirm a diagnosis of thrombocythemia?  When patients with thrombocytosis undergo laboratory tests, platelet elevation is the most prominent performance, clinical data and statistics show that the normal parameter value of platelets are (100-300) × 109 / L, for the diagnosis of thrombocytosis, as follows: 1, primary thrombocytosis platelet count is above 600 × 109 / L, often greater than 1000 1, primary thrombocytosis platelet counts are above 600 × 109/L, often greater than 1000 × 109/L, with high cases up to 10,000 × 109/L or more; 2, secondary thrombocytosis platelet counts are mostly in the range of 400 to 1000 × 109/L, more than 1000 × 109/L is rare; thrombocytosis often has recurrent bleeding, so it is also called hemorrhagic thrombocytosis, the onset of which is mostly seen in people over 40 years of age. Clinically, thrombocythemia can be divided into two categories: primary thrombocythemia and secondary thrombocythemia.  Sometimes platelet counts alone cannot completely distinguish the type of platelets, and Western clinicians often recommend other tests, such as bone marrow aspiration. The treatment of thrombocythemia is mostly chemotherapy drugs, which can control the disease, but patients need to use the drugs for life. The diagnosis and treatment of thrombocythemia in Chinese medicine is based on the differentiation and typology of the disease, and the treatment can be based on the patient’s specific condition and specific analysis, giving evidence-based treatment, which can also receive significant results.