Glucocorticoid dose reduction should be individualized under the premise of close observation of the condition and glucocorticoid response, and the following phenomena should be noted: 1. Discontinuation reaction: When glucocorticoids are used in medium or large doses for a long time, too rapid a dose reduction or sudden discontinuation can lead to hyperalgesia-like symptoms, with the milder ones showing mental depression, weakness, loss of appetite, joint and muscle pain, and the heavier ones showing fever, nausea, vomiting and hypotension. In severe cases, fever, nausea, vomiting, hypotension, etc. In critical cases, adrenal cortical crisis may occur, which requires timely rescue. 2, rebound phenomenon: in the long-term use of glucocorticosteroids, reducing the dose too quickly or suddenly stop using can make the original disease relapse or aggravate, glucocorticosteroid treatment should be resumed and often need to increase the dose, and then slowly reduce the dose after stabilization.