Mean red blood cell volume, abbreviated MCV, is the average volume of each red blood cell, measured in fL. It is obtained by dividing the hematocrit volume per liter of blood by the number of red blood cells per liter of blood, and the normal range is 80-100 fL. MCV is a very important reference for the differential diagnosis of various anemic diseases. anemias with normal MCV are aplastic anemia, acute blood loss anemia, most hemolytic anemias, and myelopathic anemias, such as acute leukemia. anemias with MCV greater than normal are Anemias with MCV less than normal include iron deficiency anemia, dyslipidemic anemia, anemia due to chronic infection, inflammation, liver disease, malignancy, rheumatic diseases, etc.