Iodophor is a chemically synthesized antiseptic solution that is applied to the surface of the wound, so it is normal for pain to occur because it can be more or less irritating to the wound. If it is a closed wound, such as a suture wound after surgery or a skin split, the pain is not very obvious after the debridement and suturing procedure. In the case of superficial abrasions, or mucosal ulcers, the pain is still more severe in wounds that have lost the protection of the epidermis. Iodine volt among all the antiseptic solutions, the stimulation of the wound is also relatively small, the pain is not too intense, intense antiseptic solution, and hydrogen peroxide, alcohol or tincture of iodine, stimulation of the wound will be more powerful, the pain will be more obvious.