Cephalosporin, that is, cephalosporin, can kill bacteria by inhibiting the synthesis of bacterial cell wall, causing bacteria to swell and dissolve, and thus has a wide antibacterial spectrum. According to the characteristics of antibacterial drugs, cephalosporins are divided into the following five generations: 1. First-generation cephalosporins: including cefazolin sodium, cefothiophene sodium, cefadroxil, cefadroxil, cefadroxil, etc., which are commonly used clinically for Gram-positive bacterial infections and penicillin-resistant Staphylococcus aureus infections; 2. Second-generation cephalosporins: including cefuroxime, cefaclor, cefotiam, etc., which are mainly used clinically for Gram-negative bacterial infections; 3, Third-generation cephalosporins: including cefotaxime sodium, cefazoxime sodium, cefoperazone, ceftriaxone, etc., effective for Enterobacter spp., Serratia spp. and gonococcus, and can be used for urinary tract infections and serious infections such as sepsis, meningitis and pneumonia; 4. Fourth-generation cephalosporins: including cefepime, effective for both gram-negative and gram-positive bacteria, and can be used for infections caused by Staphylococcus aureus, Streptococcus, Pseudomonas aeruginosa, Haemophilus influenzae pneumonia, bacteremia, sepsis, etc. caused by Haemophilus, etc.; 5. Fifth generation cephalosporins: including ceflorin, etc., which have stronger effects on Gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae, etc., mainly used for diabetic foot infection and acquired pneumonia caused by Gram-negative bacteria.