Side effects after hepatic artery perfusion chemotherapy may appear catheter-related complications, damage to the stomach and intestines, and damage to multiple organ functions. 1. Catheter-related complications: when performing hepatic artery perfusion chemotherapy operation, there may be injuries related to surgical operation, such as arterial injuries, gastric or duodenal misperfusion, decannulation, and blockage of the catheter. 2. Gastrointestinal damage: when hepatic artery perfusion chemotherapy is performed through the abdominal artery and hepatic artery, chemotherapy drugs will have gastrointestinal toxic side effects, which may cause excessive secretion of gastric acid, nausea, vomiting and other digestive symptoms. 3. Multiple organ function damage: due to the use of large doses of chemotherapeutic drugs, bone marrow suppression will occur, which is manifested in the decline of white blood cells and platelets; at the same time, liver and kidney function will also be impaired. Therefore, although hepatic artery infusion chemotherapy can effectively fight against liver cancer and inhibit tumor growth, it is necessary to pay attention to the side effects after chemotherapy to avoid aggravation of the disease.