Left shoulder and back pain, epigastric rebound pain on pressure, elevated urine amylase, the more common causes are due to poor drainage caused by gallstones, pancreatitis or pancreatic cancer, gastric ulcer and other causes. 1. Symptoms of pancreatitis include rebound pain in the abdomen and elevated amylase in the blood and urine. 2. Pancreatic cancer symptoms are also mainly abdominal pain, abdominal distension, indigestion and other symptoms. Obstructive jaundice may occur, and blood or urine tests may show elevated amylase. 3. Gastric ulcer is also characterized by abdominal pain, and severe symptoms may cause pressure pain and rebound pain. Left shoulder and back pain, epigastric pressure rebound pain, urinary amylase elevation can also be seen in other diseases, the discomfort must be timely consultation, further related laboratory tests such as blood tests, x-ray, abdominal ultrasound, etc. to clarify the diagnosis, and comply with the doctor’s instructions and active treatment, so as to avoid delaying the condition.